Tatemitsu Rai Selected Research

Chronic Renal Insufficiency

10/2023	Association of Admission Functional Status and Body Mass Index with Mortality in Patients Receiving Chronic Dialysis: A Nationwide Observational Cohort Study.
1/2023	Absence of ULK1 decreases AMPK activity in the kidney, leading to chronic kidney disease progression.
1/2023	Circulating Extracellular Vesicle-Propagated microRNA Signature as a Vascular Calcification Factor in Chronic Kidney Disease.
5/2021	Deletion of Alox15 improves kidney dysfunction and inhibits fibrosis by increased PGD2 in the kidney.
1/2020	Renal TNFα activates the WNK phosphorylation cascade and contributes to salt-sensitive hypertension in chronic kidney disease.
1/2019	Tolvaptan activates the Nrf2/HO-1 antioxidant pathway through PERK phosphorylation.
1/2018	Loop diuretics are associated with greater risk of sarcopenia in patients with non-dialysis-dependent chronic kidney disease.
1/2018	WNK1 regulates skeletal muscle cell hypertrophy by modulating the nuclear localization and transcriptional activity of FOXO4.
6/2017	The use of vitamin D analogs is independently associated with the favorable renal prognosis in chronic kidney disease stages 4-5: the CKD-ROUTE study.
2/2017	Combination of low body mass index and serum albumin level is associated with chronic kidney disease progression: the chronic kidney disease-research of outcomes in treatment and epidemiology (CKD-ROUTE) study.

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Tatemitsu Rai Research Topics

Disease

24	Pseudohypoaldosteronism 12/2018 - 10/2006
13	Hypertension (High Blood Pressure) 01/2023 - 10/2006
12	Chronic Renal Insufficiency 10/2023 - 03/2012
6	Hyperkalemia 01/2020 - 07/2005
4	Fibrosis (Cirrhosis) 01/2023 - 10/2017
4	Renal Insufficiency (Renal Failure) 01/2021 - 01/2016
4	Nephrogenic Diabetes Insipidus 12/2018 - 09/2006
3	Hypotension (Low Blood Pressure) 01/2023 - 10/2009
3	Hypokalemia 01/2019 - 10/2009
3	Alkalosis 01/2019 - 10/2009
3	Hypertrophy 01/2018 - 04/2005
3	Inborn Genetic Diseases (Disease, Hereditary) 01/2017 - 06/2013
2	Proteinuria 01/2024 - 11/2013
2	Glomerulonephritis 12/2023 - 06/2013
2	Bartter Syndrome (Syndrome, Bartter) 01/2021 - 01/2019
2	Interstitial Nephritis (Tubulointerstitial Nephritis) 01/2021 - 06/2013
2	Nephrotic Syndrome (Syndrome, Nephrotic) 01/2021 - 11/2013
2	Bacteremia 06/2019 - 11/2018
2	Brain Diseases (Brain Disorder) 06/2019 - 01/2015
2	Sarcopenia 01/2018 - 01/2017
2	Diabetes Mellitus 01/2018 - 01/2018
2	Multiple Myeloma 10/2017 - 01/2016
2	Sarcoidosis (Schaumann Disease) 11/2015 - 11/2013
2	Acidosis 10/2014 - 10/2006
2	Dehydration (Water Stress) 12/2008 - 08/2005
2	Ischemia 08/2006 - 12/2005
2	Acute Kidney Injury (Acute Renal Failure) 08/2006 - 12/2005
1	Pulmonary Embolism 01/2024
1	Syphilis 12/2023
1	Vascular Calcification 01/2023
1	Inflammation (Inflammations) 05/2021
1	Renal Cell Carcinoma (Grawitz Tumor) 01/2021
1	Wounds and Injuries (Trauma) 01/2021
1	Lipoid Nephrosis (Glomerulonephritis, Minimal Change) 01/2021
1	Acute Tubulointerstitial Nephritis 01/2021
1	Sepsis (Septicemia) 12/2020
1	Myasthenia Gravis 06/2019
1	Polyuria 01/2019
1	Autosomal Dominant Polycystic Kidney (ADPKD) 01/2019

Drug/Important Bio-Agent (IBA)

22	Phosphotransferases (Kinase)IBA 01/2020 - 10/2006
15	Lysine (L-Lysine)FDA Link 01/2020 - 12/2008
9	Proteins (Proteins, Gene)FDA Link 12/2023 - 06/2002
6	SaltsIBA 01/2020 - 08/2012
6	SodiumIBA 01/2020 - 10/2012
6	Alanine (L-Alanine)FDA Link 01/2020 - 10/2012
6	Proline (L-Proline)FDA Link 01/2020 - 10/2012
4	PotassiumIBA 01/2020 - 07/2005
3	Prednisolone (Predate)FDA LinkGeneric 01/2024 - 11/2013
3	Biomarkers (Surrogate Marker)IBA 01/2023 - 12/2005
3	DiureticsIBA 01/2021 - 01/2016
3	Sodium Chloride SymportersIBA 01/2020 - 01/2018
3	AntibodiesIBA 06/2019 - 11/2013
3	ChloridesIBA 01/2019 - 12/2015
3	Vasopressins (Vasopressin)IBA 01/2019 - 11/2016
3	Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)IBA 11/2015 - 09/2013
3	Aquaporin 2IBA 06/2013 - 09/2006
3	Glycerol (Glycerine)FDA LinkGeneric 08/2006 - 04/2005
2	Adenine FDA LinkGeneric 01/2023 - 01/2018
2	Fibrinogen (Factor I)FDA Link 06/2019 - 06/2017
2	Factor XIII (Coagulation Factor XIII)IBA 06/2019 - 06/2017
2	Immunoglobulin G (IgG)IBA 06/2019 - 06/2017
2	Member 3 Solute Carrier Family 12IBA 01/2019 - 11/2015
2	Cullin Proteins (Cullins)IBA 12/2018 - 10/2015
2	Sodium Potassium Chloride Symporter Inhibitors (Loop Diuretics)IBA 01/2018 - 01/2017
2	Bortezomib (Velcade)FDA Link 10/2017 - 01/2016
2	Aquaporins (Water Channels)IBA 06/2013 - 12/2009
2	Triglycerides (Triacylglycerol)IBA 12/2012 - 04/2005
2	Cisplatin (Platino)FDA LinkGeneric 08/2006 - 12/2005
1	Fibronectins (Fibronectin)IBA 01/2024
1	Penicillins (Penicillin)FDA Link 12/2023
1	AMP-Activated Protein KinasesIBA 01/2023
1	sacubitril and valsartan sodium hydrate drug combinationIBA 01/2023
1	Angiotensin Receptor AntagonistsIBA 01/2023
1	pro-brain natriuretic peptide (1-76)IBA 01/2023
1	azilsartanIBA 01/2023
1	MicroRNAs (MicroRNA)IBA 01/2023
1	LipidsIBA 05/2021
1	EnzymesIBA 05/2021
1	Prostaglandin D2IBA 05/2021
1	Collagen Type I (Type I Collagen)IBA 05/2021
1	Sorafenib (BAY 43-9006)FDA Link 01/2021
1	Tyrosine Kinase InhibitorsIBA 01/2021
1	GlucocorticoidsIBA 01/2021
1	CytokinesIBA 12/2020
1	sodium-calcium exchanger 1IBA 01/2020
1	SEA 0400IBA 01/2020
1	Ceftriaxone (Ceftriaxon)FDA LinkGeneric 06/2019
1	Anti-Bacterial Agents (Antibiotics)IBA 06/2019
1	Third Generation CephalosporinsIBA 06/2019
1	Cephalosporins (Cephalosporin Antibiotics)IBA 06/2019
1	Cholinergic ReceptorsIBA 06/2019
1	Tryptophan (L-Tryptophan)FDA Link 06/2019
1	4- hydroxy- 3- (4- (2- hydroxyphenyl)phenyl)- 6- oxo- 7H- thieno(2,3- b)pyridine- 5- carbonitrileIBA 01/2019
1	Calcineurin InhibitorsIBA 01/2019
1	Tacrolimus (Prograf)FDA LinkGeneric 01/2019

Therapy/Procedure

7	Renal Dialysis (Hemodialysis) 01/2023 - 02/2011
2	Protein-Restricted Diet (Diet, Protein Restricted) 01/2019 - 03/2012
2	Therapeutics 01/2016 - 07/2013
2	Sodium-Restricted Diet (Diet, Sodium Restricted) 08/2011 - 10/2009
1	Activities of Daily Living (ADL) 10/2023